MICROBIAL FOUNDATIONS
Cell Culture & Microbiology
Optimizing cellular ecosystems and bioproduction lines through high-fidelity simulation.
Engineering Biological Efficiency
The transition from lab-scale microbiology to industrial bioproduction is a challenge of data-driven optimization. Malgukke provides the HPC clusters and AI pipelines necessary to analyze complex microbial interactions and engineer high-yield cell lines for the pharmaceutical and food industries.
Microbiome Analysis
Mapping the complex interactions within microbial ecosystems to unlock new therapeutic and agricultural pathways.
Metagenomic Profiling:
Analyzing complex microbial communities to identify metabolic pathways and community dynamics.
Ecological Modeling:
HPC-simulated interactions between species to predict stability and response to environmental stressors.
Bioproduction Engineering
Optimizing the cellular "factories" of tomorrow through computational design and CRISPR-modeling.
Cell Line Optimization:
Computational modeling of metabolic flux to increase the yield of monoclonal antibodies and vaccines.
CRISPR Modeling:
Simulating off-target effects and efficiency of genetic modifications in industrial production strains.
Microbial Logic: From Culture to Industrial Value
| Research Phase | HPC / AI Action | Industrial ROI |
|---|---|---|
| Microbiome Mapping | Shotgun metagenomic assembly on high-memory nodes. | Discovery of novel probiotics and enzymes. |
| Strain Engineering | Flux Balance Analysis (FBA) using linear programming at scale. | Maximizing cellular metabolic efficiency. |